Frame Transfer Charge Coupled Device (FTCCD) is mainly used for visible light detection, which is prone to bloom in strong light applications. To solve this problem, a frame transfer vertical anti-blooming CCD image sensor is developed. The array size of the device is 1024 × 1024, and the pixel size is 12 micron × 12 micron. In order to realize the vertical anti-blooming function, an n-type buried channel saddle p-well-n-type substrate structure is adopted. The vertical anti-blooming ability is 200X, the full capacity is no less than 200ke-, the readout noise is no more than 80e-, and the dynamic range is no less than 2000:1 were achieved.