The reasonable design of the microstructure can effectively improve the heat dissipation performance of the microchannel radiator. In this paper, a microchannel radiator with droplet like microstructure is designed, and the influence of the number and height of the droplet like microstructure on the pressure loss and heat dissipation performance of the microchannel is studied by simulation method. In this paper, under the condition that the heat flux is 100W/cm^2 and the fluid velocity at the inlet is 1m/s, 9 groups of different microchannels with droplet like microstructure are designed. Five groups were studied by changing the number of droplet like microstructures in a single microchannel. It was found that when the number of microstructures was 7, the comprehensive heat dissipation performance of the microchannel was the best, and the average temperature of the bottom of the microchannel decreased by 18.42K, and the heat dissipation coefficient increased by 37.63%. At the same time, four groups of microchannels were designed based on the number of 7 microstructures to study the influence of the height of the microstructures on the heat dissipation performance of the microchannels. When the height of each microstructure in the microchannels increased along the flow direction, the heat dissipation coefficient of the microchannels was basically unchanged, while the pressure loss was reduced by 11.93%.