In PIND test，the detection probability of remainder particles in empty sealed optocoupler is of great significance to the detection effect and device reliability. In this paper, a model of PIND detection probability analysis based on voltage sampling data is proposed. After making test samples according to the common types of remainder particles and sampling, the research shows that the detection probability of short gold wire is stable and far greater than that of ceramic particles and conductive adhesive particles when they collide with ceramic inner surface, but the detection probability of conductive adhesive particles is obviously improved after increasing test frequency. Based on this, the measures to strengthen the control and detection of remainder particles are put forward. The analysis model and research method can be extended to research of PIND detection probability in other empty sealed components.